Objective: Idiopathic dilated cardiomyopathy (IDCM), one of the most major causes of chronic heart failure, is a disorder that causes impairment of the systolic function due to left ventricular dilatation without coronary artery disease. In this study, we aimed to investigate retinal vascular density (VD) changes and foveal avascular zone (FAZ) area in patients with IDCM using optical coherence tomography angiography (OCTA).
Materials and Method: Forty-eight patients with IDCM and a left ventricle ejection fraction (LVEF) below 50% (Group 1) and 50 healthy indivuals (Group 2) were evaluated via OCTA. FAZ area, superficial and the deep parafoveal VDs and peripapillary area VDs were measured and compared between the groups.
Results: The FAZ values were significantly higher in Group 1(0.29 ± 0.09, 0.20 ± 0.05; P < 0.001, respectively). Moreover, the mean VD values were significantly lower in the deep capillary plexus (DCP) of the parafoveal area in Group 1 (49.05 ± 3.81, 54.81 ± 2.88; P < 0.001, respectively). The mean VD values were also significantly lower in the peripapillary area in Group 1 (50.54 ± 3.38, 54.66 ± 1.42; P < 0.001, respectively).
Conclusion: OCTA may possess the potential to be used in the follow-up of this patient group.
Keywords: Microvascular density, dilated cardiomyopathy, heart failure, optical coherence tomography angiography
Key words: Microvascular density, dilated cardiomyopathy, heart failure, optical coherence tomography angiography
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