Periodontitis is a common immune-inflammatory oral disease. Salivary biomarkers could be a viable addition to their routine if a simple, non-invasive collection procedure is employed to minimize the disease load. Biomarkers including, matrix metalloproteinase-8, salivary interleukin-1β, and Porphyromonas gingivalis, pyridinoline cross-linked carboxyterminal telopeptide of type I collagen all have elevated incidence in the study populations and are closely connected to periodontitis. Herein, we reviewed the recent literature about periodontitis diagnostic technologies that are quick and non-invasive in clinical settings. A web-based article search by different databases like Directory of Open Access Journals, PubMed, Scopus, Google Scholar, Embase, and Cochrane electronic databases was done.
Key words: Rapid, Non-invasive, Salivary, Periodontitis, Screening
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