Abstract

Background: In the assessment of female infertility, prolactin and thyroid hormone measures, notably thyroid-stimulating hormone (TSH), have been regarded as essential milestones. Numerous elements of pregnancy and reproduction are impacted by thyroid dysfunction.

Aims and Objective: To compare the levels of thyroid hormones with those of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin in women of reproductive age who are infertile.

Materials and Methods: In this retrospective study, 50 fertile women between the ages of 20 and 45 are compared to 110 infertile women who visit our institute’s Gynec OPD. There were 110 infertile women, of which 40 had secondary infertility and 70 had primary infertility. Using chemiluminance immunoassay, the levels of thyroid hormones and infertility hormones are assessed in all individuals.

Results: TSH and prolactin had a favorable correlation with one another. In groups of infertile women, they had a negative correlation with LH, FSH, and T3. Therefore, we can conclude that the etiopathogenesis of infertility is strongly influenced by hyperprolactinemia and hypothyroidism.

Conclusion: Hypothyroidism is highly prevalent in infertile females in the current study. Menstrual abnormalities brought on by these illnesses may result in infertility. In addition connected to hyperprolactinemia, these individuals frequently experience ovulatory failure. Therefore, the evaluation of serum TSH and prolactin levels is necessary for all infertile women to undergo, especially those who report with menstrual abnormalities.

Key words: Prolactin; Infertility; Thyroid Hormones; Follicle-Stimulating Hormone; Luteinizing Hormone; Infertility