Abstract

Background: Although various drugs have been used in the treatment of COVID-19 infections, specific drug with good therapeutic outcome is still unclear. They are using remdesivir, favipiravir, ivermectin, azithromycin, and so on.

Aim and Objectives: This study aimed to evaluate the clinical profile of patients treated with different regimens and their outcome in improvement or morbidity of patients.

Materials and Methods: We conducted a cross-sectional questionnaire-based study after approval by the institutional ethics committee. Data were collected from case files of COVID-19-positive patients treated in COVID-19 ward in Bharati Hospital, Sangli. We collected the data as per our protocol proforma as – routine covid treatment with remdesivir, favipiravir and non-antiviral drugs. We analyzed various clinical profiles (presenting complaints), duration of stay in COVID wards, their outcome as improved and discharged, or deaths occurred.

Results: It was observed that majority 54% of patients were from 40 to 50 years’ range. There was male preponderance 64%. Clinical symptoms were fever (92%), cough (85%), sore throat (77%), headache (53%), and breathlessness (10%). Majority of them were diabetes mellitus (51%), obesity (22%), and hypertension. Ventilatory support treatment needed in 18%, rest of them recovered on pharmacotherapy.

Conclusion: One of the highly infectious diseases causing COVID-19 is contagious and transmitted through airborne droplets generated by sneezing, smooching, and coughing. Hence as per WHO and CDC guidelines, wear masks & avoid close contact with infected persons in public place. Vaccines available against COVID-19 Covishield and Covaxin to prevent the severity and to have immunity against COVID should be taken by all.

Key words: COVID-19; Remdesivir; Favipiravir; Antiviral Drugs