A pilot study to evaluate the effect of HAART on gonadal dysfunction in male HIV patients

Natl J Physiol Pharm Pharmacol. 2015; 5(1): 33-35

doi: 10.5455/njppp.2015.5.120720142

Abhishek Pathak, Lalit Prashant Meena, Jaya Chakravarty, Madhukar Rai, Shyam Sundar.

Abstract			Cited by 12 Articles
Background: Derangement of gonadal functions has been reported in association with HIV infection, but data from Indian population are not sufficient. Aims & Objective: To evaluate the effect of highly active antiretroviral therapy (HAART) on the gonadal dysfunction in male HIV patients. Materials and Methods: A total of 45 male HIV-positive patients were included and divided in two groups on the basis of CD4 cell count. Patients in groups A and B had CD4 count ≤200 and >200 cell/μL, respectively. Baseline hormone level was measured before the start of HAART, and the patients were followed up for 6 months and the hormone levels were measured again. Results: In group A (n = 29), six (20.69%) patients had testosterone level Key words: Highly Active Antiretroviral Therapy (HAART); Human Immunodeficiency Virus (HIV); Endocrine Changes