The current study assessed the protective role of vitamin E in alleviating the detrimental effect of nicotine on reproductive functions in male rats. Twenty four male albino rats were divided into four groups of six rats. Control group was treated orally with 1.1 ml/kg body weight normal saline, nicotine treated group received 1.0 mg/kg body weight of nicotine, vitamin E treated group received 100 mg/kg body weight of vitamin E while nicotine plus vitamin E treated group received 1.0 mg/kg body weight of nicotine plus 100 mg/kg body weight of vitamin E. The administration of nicotine and vitamin E were done orally for 40 days. Nicotine caused a significant reduction (p
Key words: Nicotine, Vitamin E, Sperm toxicity, FSH, LH, Testosterone
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