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Original Article

J App Pharm Sci. 2015; 5(9): 056-061


Antioxidant enhancing ability of different solvents extractable components of Talinum triangulare in some selected Tissue homogenates of Albino Rats -In vitro

Olakunle Bamikole Afolabi, Omotade Ibidun Oloyede, Isreal Idowu Olayide, Tajudeen Olabisi Obafemi, Obabiolorunkosi Joseph Awe, Blessing Ariyo Afolabi, Amos Sunday Onikani.




Abstract

Antioxidant contents, mostly from plant source have been the major combating components against membranous peroxidation that causes degenerative diseases and among others in the living cells. In this work, we did look into how ethanol and aqueous extractable components of Talinum triangulare could effectively and synergistically enhance the activities of antioxidant enzymes i.e superoxide dismutase (SOD) catalase (CAT) and reduced glutathione (GSH) activities in the different tissues used in vitro. Different methods were employed in the assay and the results showed significant (p < 0.05) increase in ethanolic extract when the GSH enhancing competencies were considered in the organs when compare to that of aqueous and relatively to the control test, also, the levels of catalase activities (CAT) observed showed significant (p < 0.05) difference has observed in the organs. Considering the superoxide dismutase (SOD) activities, aqueous extract showed significant (p < 0.05) increase in the liver and brain while significant (p < 0.05) increase was only observed in the ethanolic extract in the kidneys tissue. Indisputably, it could be claimed based on these facts that, Talinum triangulare might enhance the activities of the antioxidant enzymes assayed for which in turns could be helpful in the phytotherapeutic management of common diseases when involve in the diet.

Key words: Antioxidants, Talinum Traingulare, Catalase, Superoxide dismutase, Reduced Glutathione






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