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Original Article

J App Pharm Sci. 2015; 5(9): 115-119


Antimicrobial efficacy of Althaea officinalis Linn. seed extracts and essential oil against respiratory tract pathogens

Shiv Shanker Gautam, Navneet, Sanjay Kumar, Reshu Chauhan.




Abstract

In present study, Althaea officinalis seed extracts and essential oil were screened for antimicrobial activity against five bacteria and one fungi responsible for dominant, lethal or opportunistic infection of respiratory regions. The maximum inhibition was noted by essential oil against Streptococcus pyogenes (21.3±0.28 mm) and Haemophilus influenzae (19.0±0.50 mm) at 200 mg/ml. The minimum inhibitory concentration values for methanol extract was 3.12- 12.5 mg/ml. The antifungal activity noted highest with 41.28% by essential oil and 36.27% inhibition by aqueous extract represented by dosage-response curve.

Key words: Althaea officinalis, antimicrobial, dosage-response curve, minimum inhibitory concentration, respiratory tract infections






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