Objective: Bowen’s disease described by bowen originally in 1912 is an intradermal squamous cell carcinoma. We
aimed to discuss a case of bowen’s disease with uncommon presentation in the light of recent literature.
Observation a 65-year-old male presented with a lesion over the skin of the abdomen for 5-6 years duration. The
lesion gradually enlarged over the years and was asymptomatic. It had been treated and misdiagnosed by different
centers, which had resulted in partial regression; however, it started to enlarge again. Dermatologic examination
revealed a plaque, 7cm×7cm in size, on the right side of the umbilicus. It was well defined, and erythematous,
pigmented, with firm papules of various sizes at the periphery and center of the lesion. Histopathology showed
that the lesion was extending through the whole thickness of the epidermis. The basement membrane zone was
intact. Keratinocytes showed a loss of polarity and atypia. A diagnosis of "bowen's disease" was made, the lesion
was surgically excised, and skin grafting was performed.
Conclusion: Bowen’s disease should be considered when a skin lesion not responded to treatment or lesion
mimics papulosquamous disorders.
Key words: Bowen’s Disease, Skin, Dermatopathology
|
