Plasma Homocysteine Levels in Patients with Atherosclerotic Coronary Artery Disease
Bektaş Battaloğlu*, Nevzat Erdil*, Vedat Nisanoğlu*, Feridun Koşar**, Kazım Şahin***, Elif Özerol***, İsmail Temel***
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Abstract
Inherited disorders of amino acid metobolism or homocysteine metobolism have been implicated in the pathogenesis of vascular disease. The authors investigated the clinical significance of homocysteine level determination in diagnosis of coronary artery disease (CAD). The study patients (n=80), based on angiographic results, were categorized as a normal coronary group (n=30) and a CAD group (n =50). Patients with coronary artey disease had a higher homocysteine level than control subjects (19.47 ±7.13 vs 9.21±5.14 nmol/ml, p
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