The Comparison of Ferrous Sulphate and Ferric Polymaltose Treatment Efficacy of Iron Deficiency Anemia
Tamer Elkıran*, Harika Çelebi**, Bilge Aygen*
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Abstract
Background: The effect of ferric polymaltose in therapy of iron deficiency anemia is disputatious. In a prospective, randomised study, a bivalent iron salt (ferrous sulphate) was compared with a trivalent ferric hydroxide complex (ferric polymaltose) to compare treatment efficiancy and side effects.
Material and Methods: A total 60 females diagnosed as having iron deficiency anemia with clinical and laboratory findings are divided into two groups. Ferrous sulphate (160 mg /daily) was given to one group and ferric polymaltose (160 mg/daily) was given to the other for six weeks. Hemoglobin, mean corpuscular volume, transferrin saturation and serum ferritin level were studied in both groups before and after therapy.
Findings: Hemoglobin was increased in the group with ferrous sulphate therapy, but no statistical difference was found on mean corpuscular volume, transferrin saturation and serum ferritin level between two groups.
Conclusion: Ferrous sulphate threapy elevated the hemoglobin level in a shorter time than ferric polymaltose therapy.
Key words: Iron deficiency anemia, Ferrous sulphate, Ferric polymaltose
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