The Effect of Interleukin-2 on Natural Suppressor Activity of Bone Marrow and Peripheral Stem Cell Products from Patients with non- Hodgkin s Lymphoma
İ.Halil Özerol1, MD, Mustafa Şenol2, MD, Ana Ageitos1, MD, James E. Talmadge1
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Abstract
The activity of natural suppressor (NS) cells of peripheral stem cell (PSC) and bone marrow (BM) products from 24 patients with non-Hodgkin's lymphoma (NHL) were examined both before and following 5 days co-incubation with IL-2. This study showed that in the PSC products prior to IL-2 incubation, NS activity had been higher than both normal peripheral blood leukocytes (PBL) and BM products (p
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