Damage to intima of the vein, stasis of the blood, and tendency for coagulation are the main factors in development of deep venous thrombosis, particularly after surgery. Deep venous thrombosis was identified in 30 to 60% of the cases following operations by utilizing 125I fibrinogen labeling of the thrombus. The thromboembolic diseases occuring after surgery are the main factors for morbidity and mortality. The most common signs of deep venous thrombosis are swelling, tenderness of the foot, and the Homans' sign. Phlebography and Doppler ultrasound are important diagnostic tools. Mechanical preventions such as application of elastic bandages to avoid development of thrombus are useful. Prophylactic subcutaneous heparin is administered 2 hours before and 8-12 hours after the operation. Recently the use of low-molecule heparin is becoming popular. Oral anticoagulant treatment for 6 months is necessary in order to prevent recurrences. Nevertheless, the key points to prevent occurrence of thromboembolic events are determination of the risk factors and application of the optimal prophylaxis. [Journal of Turgut Ozal Medical Center 1998;5(1):105-109]
Key Words: Thromboembolic events, prophylaxis, heparin
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