When suspecting an allergic disease, it should be confirmed using special tests. In this study, 79 patients who were followed up by outpatients of Allergy of Dr. Behçet Uz Children's Hospital was examined. Twenty healthy children served as the control group1 We aimed to determine the importance of skin tests by comparing specific IgE and total IgE levels by EIA of patients having allergic complaints1 The 59% (47) of the patients was male and 41 %(32) female. Average age was 107.55 ±27.82 months.The 65%(13) of the control group was male, 35%(7) female and the average age was 108.5 ±24.5 months.Patients were dispersed in a broad range diagnosis spectrum from Asthma Bronchiale (AB) to AB+allergic rinit, urticaria, allergic conjunctivitis. Levels of total and specific IgE were determined/ scratch and intradermal skin tests were performed to the patients. Total and specific IgE levels of the control group were studied. In laboratory findings which were made for supporting the diagnosis, 59°% was positive for total IgE, 52°% and 85°% was positive for scratch and intradermal skin tests respectively. Specific IgE levels were found 71% positive. In our study, while the sensitivity and specifity of total IgE were found 58.2% and 33.3% respectively, for specific IgE, they were found 80.5% and 83.3%. Since specific IgE which was determined by ELISA method was found highly specific and effective, we can easily claim that it is a reliable diagnostic technique which can be used in the diagnosis ofallergic diseases.
Key words: ELISA, total IgE, specific IgE, skin tests, allergy
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