Bone marrow transplantation in the treatment of solid tumors
Dr. Süleyman Büyükberber*, Dr. N. Mehmet Büyükberber**, Dr. Orhan Şencan*, Dr. V. Akın Uysal***
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Abstract
In the last ten years, autologous bone marrow transplantation in the treatment of malignant disease has been increasingly used. This procedure is limited to the 20-25 % of the cases where HLA-ABC and DR tissue groups are suitable for performing allogeneic bone marrow transplantation. Therefore, in the cases in whom conventional dose chemotherapies can not provide a complete remission, high-dose chemotherapies have often been used through autologous bone marrow transplantation. This therapy has been performed in malignancies such as lymphomas, multiple myelomas, small cell lung cancers, ovarian and germ cell cancers, neuroblastomas, malignant melanomas, rhabdomyosarcomas, Ewing sarcomas and breast cancers recently.
Key words: Cancer, chemotherapy, autologous bone marrow transplantation
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