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Case Report

J Med Allied Sci. 2025; 15(1): 85-87


NUDT15 polymorphism-induced severe neutropenia in a young male with precursor T-cell acute lymphoblastic leukemia

Jignesh Bharat Patel, Krishna K. Lakhani, Roma K. Desai.



Abstract
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The management of acute lymphoblastic leukemia (ALL) involves intensive chemotherapy which can lead to significant myelosuppression. Here we present a case of ALL who experienced severe neutropenia during maintenance therapy due to a NUDT15 polymorphism.

Key words: Acute lymphoblastic leukemia, Mercaptopurine, NUDT15, Thioguanine

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0708091011120102
20252026

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