Introduction: Epithelioid Hemangioendothelioma (EHE) is a rarely seen tumor most frequently originating
from vascular structures of different regions including liver, followed by stomach, spleen, lung, bone, soft
tissue, and skin.
Case Presentation: In this paper, a patient with multiple mass lesions in the liver with a diagnosis of EHE who underwent liver transplantation is presented.
Conclusion: It has an intermediate degree of malignancy between benign hemangioma, and malignant hemangiosarcoma. It can manifest with nonspecific symptoms or hepatic failure. Generally it is seen as a diffuse hepatic disease. The most optimal treatment alternatives are liver resection, and transplantation.
Key words: Hemangioendothelioma, liver transplantation, liver tumor
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