Abstract

Background: Thyroid disorders (hypothyroidism and hyperthyroidism) are a widespread thyroid problem, but there are no reports on the incidence and prevalence of thyroid disorders in this part of Western Uttar Pradesh of India.

Objective: The aim of this study was to assess the prevalence of thyroid disorders in Firozabad and its adjoining areas.

Materials and Methods: This retrospective hospital-based study involved 982 patients having undergone thyroid function assay, in the central clinical biochemistry laboratory of F. H. Medical College and Hospital, Firozabad. Firozabad is a city in western Uttar Pradesh of India about 40 km from Agra. These patients were evaluated for thyroid hormonal assay- total tri iodo thyronine (T3), total tetra iodo thyronine (T4), and thyroid stimulating hormone (TSH) by Vidas auto analyzer using enzyme-linked fluorescent assay technique. Statistical analysis was performed by SPSS version 17 software.

Result: Our study shows high prevalence of abnormal thyroid hormone levels (hypothyroidism including subclinical hypothyroidism 43% and hyperthyroidism was 26%) with female preponderance.

Conclusion: The study has defined thyroid function status in thyroid patients of Firozabad, Uttar Pradesh, India. Higher prevalence of hypothyroidism was observed in patients (especially females) in third decade of life. The findings also support the indication of thyroid hormone screening during third decade of life and afterwards.

Key words: Thyroid disorder, hypothyroidism, subclinical-hypothyroidism, TSH