Abstract

Mitral valve prolapse (MVP) is generally known as a benign disease with a good prognosis. Patients with the arrhythmic MVP (AMVP) phenotype have an increased risk of ventricular arrhythmia and sudden cardiac death. The frontal QRS-T angle is a new indicator, related to malign arrhythmias and cardiac death risk in various diseases. This study aimed to compare the frontal QRS-T angle of patients with MVP without the AMVP phenotype with that of healthy subjects. Fifty MVP patients without the AMVP phenotype, identified through a retrospective review of medical records, constituted the MVP group, and 50 healthy individuals constituted the control group. Frontal QRS-T angle and other electrocardiography and echocardiography parameters were compared between the groups. The groups were similar in terms of demographic characteristics and laboratory results. Frontal QRS-T angle was similar in both groups (30±37° vs 28±24°, p=0.56). There was also no difference in other electrocardiographic and echocardiographic parameters between the groups. In MVP patients without the AMVP phenotype, the frontal QRS-T angle does not change compared to healthy individuals. The risk of ventricular arrhythmia and sudden cardiac death in this patient population appears to be similar to that in healthy individuals.

Key words: Electrocardiography, cardiac arrhythmias, arrhythmic mitral valve prolapse, frontal QRS-T angle, myocardial repolarization