Abstract

Pulmonary Blastoma is a rare malignant lung tumor. The Biphasic pulmonary blastoma is composed of a mixture of immature epithelial and mesenchymal tissue ressembling fetal lung tissue with poor prognosis . The surgery is the treatment of choice. The strategy of treatment remains unclear due to the rarity of this tumor. We report a case of 26 year old women presenting with biphasic pulmonary blastoma who was treated with surgery and 6 cycles of adjuvant chemotherapy Etoposide-Cisplatine. Before she underwent adjuvant radiotherapy due to the positive margins, she developed dyspnea and the CT scan showed a massive local recurrence tumor compressing the heart. The patient received a palliative radiotherapy in the chest at the dose of 20Gy followed by palliative chemotherapy based on Adriamycin and Ifosfamide.

Key words: Biphasic pulmonary blastoma, chemotherapy, Radiotherapy