Abstract

Background:
Primary hypothermia occurs when the body is exposed to extremely low temperatures in the enviornment with no underlying health conditions. Secondary hypothermia, on the other hand, results from disruptions in thermoregulation due to diseases, trauma, surgery, drugs, alcohol, or infections. Postmortem biochemistry has become a crucial factor in forensic examinations, offering valuable apprehension into tissue impairment and organ dysfunction connected with the process of dying

Aim:
This research aims to explore various biochemical markers and their significance for distinguishing primary hypothermia from secondary hypothermia.

Methods:
This study involved 21 Wistar rats, which were separated into three experimental groups: CG(n=7), which was exposed only with hypothermic conditions; AHG (n=7); and BHG (n=7). We tested these parameters in each rat: Glucose, Urea, Creatinine, Blood Urea Nitrogen to Creatinine Ratio, Phosphorus, Calcium, Sodium, Potassium, Sodium to Potassium Ratio, Chloride and Calculated Osmolality.

Results:
Distinct biochemical discrepancies were noted between primary and secondary hypothermia. Glucose and creatinine levels exhibited significant variations (p

Key words: Hypothermia, Forensic, Cause of death, Biochemical analysis