Skeletal muscle is an important tissue which functions as an endocrine organ and secretes the factors called myokine. Irisin is a thermogenic peptide which has been recently defined as a new myokine. The physiological roles of these peptides have been revealed in recent studies. The purpose of this review is to explain the known physiological roles of irisin.
Key words: Irisin, myokine, endocrine system, energy metabolism, physiological roles
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