The volatile constituents of Cinnamomum bejolghota bark essential oil were investigated by using gas chromatography-mass spectrometry (GC-MS). Thirty-six volatile constituents were identified with the major components being 1,8-cineole, γ-terpineol, borneol and terpinen-4-ol. Essential oil of C. bejolghota bark was firstly screened for their antibacterial and antifungal activities against Gram-positive and Gram-negative bacteria, as well as, Colletotrichum sp. fungi using disc diffusion method. Minimal inhibitory concentration (MIC) of C. bejolghota bark oil was further analyzed by microdilution. Essential oil of C. bejolghota bark was most effective against bacteria with MIC ranging from 31.25-62.50 μg/mL, whereas inhibition against fungal pathogens was moderate, with MIC of 125- 500 μg/mL. The strong antimicrobial activity of C. bejolghota bark oil was correlated mainly to 1,8-cineole, γ-terpineol, borneol, terpenen-4-ol and linalool.
Key words: Cinnamomum bejolghota, essential oil, antibacterial, antifungal, phytochemical composition, 1,8-cineole
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