Aim: This study aims to investigate the effects of topically applied tranexamic acid (TXA) on postoperative complications at the saphenous vein graft site following coronary artery bypass grafting (CABG).
Material and Methods: A prospective analysis was conducted on 63 patients who underwent CABG between January 2024 and August 2024. Patients were randomly divided into two groups: a TXA group (n=32) who received topical TXA at the saphenous vein incision site, and a control group without TXA (n=31). Outcomes evaluated included leg circumference measurements, incidence of hematoma, ecchymosis, inflammation, necrosis, surgical infection, and mobilization difficulty. Pain and quality of life were assessed using the Visual Analog Scale (VAS) and Venous Clinical Severity Score (VCSS) respectively.
Results: Patients in the TXA group exhibited significantly lower leg circumference measurements postoperatively on days 1 and 5 (p
Key words: Tranexamic acid, coronary artery bypass grafting, saphenous vein harvesting, venous clinical severity score, visual analogue scale
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