Abstract

Objective
This study aims to evaluate the maternal and fetal outcomes of cancer patients who were diagnosed during pregnancy or whose pregestational period has passed and are in remission, and to share clinical experiences in this field.
Material and Method
In this retrospective study conducted at Ankara City Hospital between January 2021 and March 2025, a total of 99 pregnancy cases were examined. The study included 18 patients diagnosed with cancer during pregnancy, 21 patients with a history of cancer in remission, and 60 healthy control pregnant women. Data were collected from patient files and clinical records, demographic information, cancer type and stage, treatment modalities, maternal and neonatal outcomes were evaluated.
Results
Breast and thyroid cancer were the most common malignancies diagnosed during pregnancy. The diagnosis was usually made in mid-pregnancy and the treatment included surgery and chemotherapy. The maternal mortality rate in these patients was 11.2%, most of which occurred in advanced stage and aggressive tumors. In terms of neonatal outcomes, infants in this group had lower birth weights and higher neonatal intensive care needs.
Conclusion
It has been shown that both maternal and infant health can be protected with surgery and chemotherapy administered at appropriate times with a multidisciplinary approach in patients diagnosed with cancer during pregnancy. Early diagnosis and appropriate treatment protocols play an important role in improving the quality of life and clinical outcomes of these patients. Further research in this area will contribute to the development of treatment strategies.
Keywords: Active cancer during pregnancy, Maternal mortality, Neonatal intensive care requirements

Key words: Active cancer during pregnancy, Maternal mortality, Neonatal intensive care requirements