Abstract

Purpose: To systematically evaluate the effectiveness of family medicine-based interventions in improving medication adherence among diabetic patients.
Methods: A systemic review was conducted using PubMed, European PMC, and DOAJ between 2015 to 2025, including adults with diabetes managed in family medicine or primary care settings. Medication adherence was the primary outcome, while glycemic control and patient-reported outcomes were the secondary measures.
Results: Out of 5,551 records, 58 studies were included from highly diverse geographic sites like China, UK, and USA, with sample sizes ranging from 40 to more than 20,000 participants. Family medicine interventions significantly improved medication adherence (pooled OR 2.14). Effective strategies included continuity of care, behavioral counseling, motivational interviewing, shared decision-making, and digital follow-up led to improved HbA1c levels, reduced diabetes distress, and increased patient satisfaction.
Conclusion: Family medicine interventions are crucial for enhancing medication adherence in diabetic patients, and contribute to improved clinical and psychological outcomes.

Key words: Diabetes mellitus, Family medicine, Primary care, Medication adherence, Intervention.