Abstract

This study aimed to investigate the impact of dietary magnesium butyrate (MgB) supplementation for three weeks pre-calving on peripartum hematological profile, immune and biochemical parameters of Holstein cows. Thirty-four dry-pregnant multi-parous Holstein cows were randomly divided into a control group that received the basal diets (BD) and MgB group that received the BD supplemented with Mg for three weeks before expected calving. No statistically significant differences (P≥0.05) were observed between the control and MgB-supplemented group for any of the measured hematological parameters or serum total protein, either in the pre-calving or post-calving periods. Pre-and post-partum cows fed on MgB-containing diet exhibited a numerical (P≥0.05) elevation of blood lymphocytes%, eosinophils%, and phagocytosis compared to the control cows. Serum liver-related enzymes (glutamic pyruvic transaminase (GPT) and glutamic-oxaloacetic transaminase (GOT)) and kidney function related parameters (uric acid and urea) were lower in MgB received group at all experimental periods with a significant (P 

Key words: Magnesium Butyrate, Hematology, Immunity, Antioxidant, Dairy Cows.