Cinnamic acid, chemically known as 3-phenyl-2-propenoic acid is has a broad spectrum of pharmacological actions including antioxidant activity. The esterification and selective reduction of the acid led to ethyl cinnamate and cinnamyl alcohol, respectively. Cinnamic acid demonstrated a poor antioxidant activity (IC50) of 1.2 µg mL-1 while ethyl cinnamate and cinnamyl alcohol elicited activities of 0.64 µg mL- 1 (moderate) and 0.84 µg mL-1, respectively. The obtained results indicate that esterification enhances the antioxidant activity of cinnamic acid.
The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.