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Original Research

TAF Prev Med Bull. 2008; 7(6): 477-484


Evaluation of the Etiological, Clinical and Laboratory Findings in Patients with Cerebral Palsy

Sebahattin,Vurucu, Oktay,Sarı, Mustafa,Gülgün, Bülent,Ünay, Rıdvan,Akın, Okan,Özcan.



Abstract
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AIM: In this study we aimed to discuss the etiological risk factors, clinical and laboratory findings of the patients with cerebral palsy (CP) according to the literature of knowledges.
METHOD: The data including sex, age, social status of families, method of delivery, type of CP, risk factors, comorbidities, brain imaging and electroencephalograpy findings were retrospectively recorded from the patients’ files.
RESULTS: A total of 180 patients were included in this study. Of the patients 58.3% were boy, 41.7% were girl, and mean age at diagnosis was 8.98±5.34 months. Of the patients 77.8% had vaginal birth, 22.2% had cesarean birth. The patients who had vaginal birth had statisticaly higher ratio of comorbidity, and lower mean diagnostic age, respectively (respectively p=0,027, p=0,031). Of the patients 88.3% had spastic CP, 10.6% had ataxic-hypotonic CP and 1.2% had other CP types. Of the patients 51,1% had at least one etiological risk factors. Most common etiological risk factors were perianal asfixi (22.7%), prematürity (15.5%), small for gestational age (7.2%) and others (18.9%). Of the patients 79.5% had at least one comorbidity. Most common comorbidities were lenguage disabilities (60%), eye abnormalities (56.6%), mental retardation (53.3%), epilepsy (41.1%) and others (12.1%). Of the patients 85.6% had at least one brain imaging abnormality. Most common brain imaging abnormalities were cortical atrophy (34.4%), abnormalities of corpus callosum (20%), periventricular leukomalacia (16.6%), encephalomalasia (10.5%), cerebral infarction (10%), hypoxic ischemic encephalopaty (6.6%) and others (11.9%).
CONCLUSİON: Most of the our patients had spastic type CP, comorbidities including lenguage disabilities, eye abnormalities, mental retardation, and epilepsy and brain imaging abnormalities including cortical atrophy, abnormalities of corpus callosum, and periventricular leukomalacia. Therefore we consider that there may be a relationship between brain imaging abnormalities and prognosis of CP.

Key words: Cerebral palsy, Etiological risk factors, Clinical findings, Laboratory findings

Article Language: Turkish English





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