Objective: Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies. There are unmet needs regarding the efficacy of nodule size in prediction for the co-existence of IMC. We aimed to measure the effect of nodule size on the prediction of the coexistence of IMC.
Method: The data of 194 patients who underwent biopsy for fine-needle aspiration cytology, and subsequent thyroidectomy in a research and training hospital between January 2017 February 2020 were analyzed, retrospectively. The patients were divided into three groups according to sizes of thyroid nodules as 0-10 mm, 11-20 mm, and >20mm. Logistic regression analysis was performed.
Results: The patients with nodule size between 0-10 mm mostly showed hypothyroidism (51.0% vs 28.8% vs 41.8%) while patients with size between 11-20 mm mostly had euthyroidism (44.2% vs 45.1% vs 41.8%, p=0.0175). Both malignancy (51.9% vs 49.0% vs 42.9%, p=0.544) and IMC (65.4% vs 51.0% vs 56.0%, p=0.32) were observed more likely in patients with moderate size (11-20 mm). We found the following variables to be predictors for the co-existancy of IMC: absence of halo [OR: 4.5095%CI: 1.61- 14.71, p= 0.007], and interestingly decrease in vascularity [OR: 0.33, 95%CI: 0.12- 0.87, p= 0.030], and total thyroidectomy, [OR: 4.55, 95%CI: 2.30- 9.56, p 2 cm) we reported more IMC inside the thyroid gland. However, the nodule size has the low performance to be a predictor for the co-existence of IMC in the thyroid gland.
Key words: Thyroidectomy, malignancy, nodule size
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