Abstract

Several novel pyridine, pyrido[2,3-d]pyrimidine and pyrido[2,3-d] 3,1-oxazine derivatives were prepared using the readily obtainable
starting material 2-amino-6-aryl-4-(3,4,5-trimethoxyphenyl) pyridine-3-carbonitrile 1a,b via the reaction with one carbon donors such as
phenylisothiocyanate, carbon disulphide and formic acid. The IR, 1H-NMR and mass spectra for the new synthesized compounds were
discussed.

Key words: pyrido[2,3-d]pyrimidines, pyrido[2,3-d]-3,1-oxazines, one carbon donors.