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Original Article

ECB. 2013; 2(9): 679-682


MICROWAVE ASSISTED EXPEDITIOUS SYNTHESIS OF BIOACTIVE POLYHYDROQUINOLINE DERIVATIVES

Vijaykumar M. Joshi, Rajendra P. Pawar.



Abstract
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A facile and green one pot four component synthesis of polyhydroquinoline derivatives from aldehydes, dimedone, ethyl acetoacetate and
ammonium acetate in the presence of a spinel (ZnFe0.2Al1.8O4) composite catalyst has been reported under microwave irradiation. The
method offers excellent yield of products in short reaction time.

Key words: polyhydroquinolines, Hantzsch’s condensation, ZnFe0.2Al1.8 O4 nanocomposite catalyst, microwave irradiation





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