Aim: In this study, the general characteristics of incidental liver metastasis and the factors affecting survival were investigated.
Material and Methods: In our study, we retrospectively analyzed 216 patients with metastases in the liver at diagnosis. Patients with previously known primary malignancy and liver failure due to chronic viral hepatitis were excluded from the study.
Results: In the overall survival analysis, a statistically significant relationship was found between albumin, AST, ALP, LDH, GGT, CA 19-9, TBIL, DBIL levels, and overall survival. Good prognostic factors for overall survival: the age of 65 and below, right hepatic lobe metastasis, solitary hepatic lesion, maximum tumor diameter is 3 cm below, and colorectal tumors. Also, there was a correlation between the presence of extrahepatic metastasis and CA-125 levels.
Conclusion: The patient age, tumor size in the liver, anatomical location of the tumor, tumor number, primary focus of the tumor, and blood tests including albumin, AST, ALP, LDH, GGT, CA 19-9, TBIL, and DBIL can be useful in predicting patient survival and prognosis.It was also found that CA-125 could be a useful marker predicting the presence of extrahepatic metastasis.
Key words: Liver metastasis, unknown primary cancer, prognosis, tumor markers
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